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Index > Protein center > FGF7(Gene name) > Human
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  • FGF7 (Gene name),
  • Keratinocyte growth factor (Protein name ),  FGF7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    FGF7(KGF);
    Protein name:
    Keratinocyte growth factor(KGF);
    Alternative:
    Heparin-binding growth factor 7(HBGF-7);Fibroblast growth factor 7(FGF-7);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
    Function:
    Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    194
    Sequence:
    50:
    MHKWILTWIL | PTLLYRSCFH | IICLVGTISL | ACNDMTPEQM | ATNVNCSSPE | 
    100:
    RHTRSYDYME | GGDIRVRRLF | CRTQWYLRID | KRGKVKGTQE | MKNNYNIMEI | 
    150:
    RTVAVGIVAI | KGVESEFYLA | MNKEGKLYAK | KECNEDCNFK | ELILENHYNT | 
    194:
    YASAKWTHNG | GEMFVALNQK | GIPVRGKKTK | KEQKTAHFLP | MAIT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    MIM:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human KGF
    Cat.:
    E0636h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human KGF
    Cat.:
    E0636r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human KGF
    Cat.:
    E0636p
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    MSDS:
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    96T
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    ELISA Kit for Human KGF
    Cat.:
    E0636m
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    96T
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    ELISA Kit for Human KGF
    Cat.:
    E0636d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human KGF
    Cat.:
    U0636m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human KGF
    Cat.:
    U0636d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human KGF
    Cat.:
    U0636p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human KGF
    Cat.:
    U0636r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human KGF
    Cat.:
    U0636h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human KGF
    Cat.:
    P0636Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human KGF
    Polyclonal Antibody for Human KGF
    Cat.:
    P0636Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human KGF
    Cat.:
    P0636Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human KGF
    Monoclonal Antibody for Human KGF
    Monoclonal Antibody for Human KGF
    Monoclonal Antibody for Human KGF
    Monoclonal Antibody for Human KGF
    Monoclonal Antibody for Human KGF
    Protein for Human KGF
    Protein for Human KGF
    Protein for Human KGF
    Protein for Human KGF
    Protein for Human KGF

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    References
    1. 1.
      "Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth."
      Finch P.W. , Rubin J.S. , Miki T. , Ron D. , Aaronson S.A.
      Science245:752-755(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 32-50
    2. 2.
      "Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity."
      Aaronson S.A. , Bottaro D.P. , Miki T. , Ron D. , Finch P.W. , Fleming T.P. , Ahn J. , Taylor W.G. , Rubin J.S.
      Ann. N. Y. Acad. Sci.638:62-77(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLU-62
      tissue: Brain.
    7. 8.
      "Purification and characterization of a newly identified growth factor specific for epithelial cells."
      Rubin J.S. , Osada H. , Finch P.W. , Taylor W.G. , Rudikoff S. , Aaronson S.A.
      Proc. Natl. Acad. Sci. U.S.A.86:802-806(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-44
    8. 9.
      "Receptor specificity of the fibroblast growth factor family."
      Ornitz D.M. , Xu J. , Colvin J.S. , McEwen D.G. , MacArthur C.A. , Coulier F. , Gao G. , Goldfarb M.
      J. Biol. Chem.271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR2;FUNCTION IN CELL PROLIFERATION
    9. 10.
      "The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair."
      Beer H.-D. , Bittner M. , Niklaus G. , Munding C. , Max N. , Goppelt A. , Werner S.
      Oncogene24:5269-5277(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFBP1
    10. 11.
      "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."
      Zhang X. , Ibrahimi O.A. , Olsen S.K. , Umemori H. , Mohammadi M. , Ornitz D.M.
      J. Biol. Chem.281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR2;FUNCTION IN STIMULATION OF CELL PROLIFERATION
    11. 12.
      "Fibroblast growth factor signalling: from development to cancer."
      Turner N. , Grose R.
      Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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